For decades, human embryos’ usage in research has spurred debates around ethics and governance. As technological advancements allow us to create increasingly realistic embryo models from pluripotent stem cells, these debates have evolved to encompass both familiar and novel ethical concerns.

At the heart of these discussions is the question of how ethical frameworks should adapt to these scientific advancements. For example, the widely adopted ‘14-day rule,’ which limits embryo culture to 14 days or the emergence of the primitive streak, may prove inadequate in the context of embryo models. Should alternative ethical boundaries be imposed on the culture of these models, and if so, what should they be? Should certain models require greater ethical scrutiny, and if so, how ought we differentiate? How can scientists and policymakers balance innovation with ethical responsibility?

Our workshop will gather experts in biomedical science, social science, and bioethics to address these critical issues. The workshop will foster an international, interdisciplinary network of experts to impact contemporary policymaking and facilitate responsiveness to future developments. Key outcomes of the project will include academic publications as well as a lay resource, contributing significantly to ongoing discourse while laying the groundwork for future collaborative efforts.

The three-day workshop will feature different speakers’ presentations, followed by open discussions, with co-applicants rotating note-taking responsibilities and chairing the break-out groups during discussions.